Bioprospecting of the Telekia speciosa: Uncovering the Composition and Biological Properties of Its Essential Oils

The essential oils (EOs) of Telekia speciosa, a perennial plant native to southeastern Europe and Asia Minor, were analyzed for their composition biological properties. T. speciosa is an invasive in Poland; however, its beauty prompts gardeners cultivate the plants. serves as valuable source nectar pollen honey bees. Our results revealed more than 150 compounds flower, leaf, root EOs. Major constituents found from roots included isoalantolacton (46.2%) flowers nerol (11.9%), while leaves, they (E)-nerolidol (10.1%). flower EO showed significant cytotoxicity against A375 cells, with IC50 values 7.2, 5.1, 3.4 μg/mL referring 24, 48, 72 h, respectively, indicating potential natural cytotoxic agent. antimicrobial activity Staphylococcus aureus ATCC 29213 Escherichia coli 25922 was also investigated. leaves demonstrated higher inhibitory S. (MIC: 5.9–7.8 μL/mL) E. 7.8–11.7 oil isolated (MICs 31.3 62.5 μL/mL coli, respectively).